MedGenome’s genomics research platform offers infrastructure and service capabilities to enable large scale genomics research. MedGenome clients can leverage our collaborator network, rich data and research informatics for accelerating basic and drug discovery research.
Infrastructure
Collaborator network for prospective studies
Access to tissue/blood samples
Sequencing and clinical data across diseases
Access to patient cohorts, biosamples, genomics and rich clinical data
Continued access to patients for follow-up and pedigree information
Services and Research Informatics
NGS Services
NGS Informatics
Point solutions and pipelines
State-of-the-art sequencing and research informatics services
Disease-specific Knowledge Databases
MedGenome’s network of large hospital collaborators and genetic centers offer sample access with archived clinical data across the following disease areas:
Genomics research studies on stratified population substructures are found to be effective
Unstratified Disease CohortCritical requirements - Access to Samples
Stratified By Clinical DataRich clinical and phenotype data
Stratified by population substructureGenomic data - Population information
Examples of disease genes discovered using defined populations:
Hypercholesterolemia (LDL receptor)
Cancer (APC, RB)
Obesity (ABC1, PCSK9)
Diabetes (PPAR-γ )
Indian population genetics is a treasure trove of information and insights
The Indian population originated from a small number of founder families
Ancestral population became heterogeneous over time due to diverse climatic and other life style conditions
Restricted gene flow between groups which created 3000 – 5000 population isolates that has preserved rare disease alleles associated with complex diseases over a period of time
Collaborator network for prospective studies
Access to tissue/blood samples
Sequencing and clinical data across diseases
NGS Services
NGS Informatics
Point solutions and pipelines
ONCOLOGY
NEUROLOGY
Cardiovascular / Diabetes
Autoimmune
Population Genomics & Longevity
Rare Inherited Diseases
Prenatal
Ophthalmology & ENT
