Long-read sequencing solutions

Long-read sequencing for multiple applications

Experience MedGenome's advanced capabilities in de novo genome assemblies, full-length transcriptome sequencing, and comprehensive variant detection with PacBio HiFi technology

While short-read sequencing has been an advantage for genomics study, it struggles to resolve repetitive regions, assemble complex structural variants, and fully capture isoform diversity. PacBio HiFi sequencing solves these issues with highly accurate long reads, enabling comprehensive profiling of genetic variation, including SNVs, Indels, SVs, and complex regions. MedGenome provides unparalleled capabilities with both short-read and PacBio long-read solutions, supporting highly contiguous genome assemblies, structural variant detection, full-length transcript sequencing, epigenetic profiling, and haplotype phasing, providing comprehensive genomic insights for diverse research needs.

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PacBio HiFi Long-read sequencing solutions

Streamlined long-read DNA and RNA sequencing workflows: unified solutions to save time and effort

De novo Genome Assembly and Annotation

Reference-quality genome assembly: highly accurate and contiguous genome assemblies.
Comprehensive genome annotation: complete and accurate gene models including identification of isoforms and alternative splicing.

Human variant detection

Unparalleled variant detection: Identify challenging structural variants and variants in complex regions of the genome.
Comprehensive genomic coverage: Uniform genome-wide coverage, minimizing biases and enabling confident variant calling in GC-rich and repetitive regions.
Haplotype resolution: Resolve variants on homologous chromosomes, providing insights into allele-specific expression and compound heterozygosity.

Full-length RNA sequencing

Isoform diversity: quantify all gene isoforms, including novel ones.
Fusion gene detection: characterize fusion genes, crucial for understanding cancer development.
Long non-coding RNA (lncRNA) analysis: identify and characterize lncRNAs, important regulatory molecules often missed by short-read sequencing.

Single-cell full-length RNA Seq

Deconvolute cellular heterogeneity: Profile full-length transcriptomes to reveal diversity and rare cell types.
Discover novel cell states: Track isoform changes for insights into differentiation and disease.
Link transcriptomic variation: Correlate isoform expression with cell markers to understand functional consequences.

Long-read sequencing analysis

Integrated bioinformatics solutions: assembly, variant detection, and comprehensive RNA analysis

With our deep bioinformatics expertise and extensive data infrastructure, we can support you from sample to answer. From genome assembly and annotation to comprehensive variant detection to transcriptome profiling, we have a long-read solution to fit your needs.

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how to order

Starting a project with MedGenome

MedGenome's customer portal allows for easy sample submission and sample tracking during lab processing. Using our portal ensures data QC, raw data and interactive analysis reports are delivered securely.

Our process is simple

Request a quote

We create your project

Upload sample details

Submit documents and ship samples

We process and analyze your samples

Your data is delivered to you

services

Other services you'll be interested in

Transcriptomics services
WGS/WES services
Immune profiling services

Transcriptomics services

Vast experience and expertise in generating high-quality data from degraded RNA samples.
Supported by custom and advanced bioinformatics analytics.

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WES/WGS

Cost effective whole genome/exome services with expedited turn-around times.

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Immuno-oncology solutions

Multi-species (human, mouse, rat and non-human primate) bulk and single cell TCR/BCR sequencing and bioinformatics services.

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TESTIMONIALS

"Always very quick responses, wonderful turnaround times and exemplary quality of service. Data is always great, and any issues are always resolved. The price is competitive, stable and reliable. There's no problem that the MedGenome team hasn't solved yet."

– Cassie Pond, The Feinstein Institutes for Medical Research

TESTIMONIALS

"We are examining the results. Very exciting. My compliments — you make the best summary report I have seen."

– Dr John Castle, Sr. Director, Bioinformatics, Agenus

TESTIMONIALS

"We have been working with MedGenome on identification of novel oncogenic mutations and exome anlaysis of tumor cells. Our collaboration has been extremely productive. We are extremely happy with their commitment towards research and development in general"

– Dr Krishnaraj Rajalingam, Heisenberg Professor in Cell Biology, Mainz University, Germany

TESTIMONIALS

"We have been working with MedGenome on genomics-based diagnostics and research for many years now. We are extremely happy and pleased with the quality, the skill and the pro-activeness of the firm. No wonder that it has grown to be a leading genomics service provider."

– Dr Radha Rama Venkatesan, Executive Scientific Officer, Molecular Genetics, MDRF

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MedGenome enhances omics insights with in-house PacBio Revio full-service capability

MedGenome, in collaboration with PacBio, announces a de novo genome assembly and annotation grant

MedGenome's genomics solutions for precision medicine

MedGenome, in collaboration with PacBio, announces a de novo genome assembly and annotation grant

Accuracy with deep insights: HiFi Long-read sequencing solutions

Experience MedGenome's advanced capabilities in de novo genome assemblies, full-length transcriptome sequencing, and comprehensive variant detection with PacBio HiFi technology