Targeted genome editing in tomato: unraveling gene regulation in carotenoid biosynthesis
As a subsidiary of MedGenome, AgriGenome leveraged its expertise in plant genomics to conduct a proof of concept study on carotenoid biosynthesis in tomatoes using CRISPR/Cas9 technology, published in Plant Cell Reports1. The research demonstrates that a controlled knockdown of genes can be achieved by targeting the regulatory regions, rather than coding regions that often have unwanted consequences of knockdown.