Filaggrin gene polymorphisms in Indian children with atopic dermatitis: A cross-sectional multicentre study

Indian journal of dermatology, venereology and leprology, Pages 1-9, 2023

PMID: 37067103

Filaggrin (FLG) gene encoding the protein filaggrin plays an important role in barrier function of the skin and its alteration is a predisposing factor for atopic dermatitis. FLG gene variants result in absent or decreased filaggrin protein. Worldwide, the prevalence of FLG variants ranges from 14 to 56%. FLG null variants are distinct in each population.

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