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Navigating the clinical landscape: Update on the diagnostic and prognostic biomarkers in multiple myeloma

Mol Biol Rep, Vol. 51, Issue 1, Article Number: 972, 2024

PMID: 39249557

Multiple myeloma, a complex hematologic malignancy, causes severe bone loss, pain, and fractures that significantly impact patients’ quality of life and survival. This article reviews current biomarkers used for diagnosis and prognosis, from traditional serum markers to advanced molecular profiling techniques, highlighting their utility and limitations. It emphasizes the role of personalized medicine in tailoring therapies and explores the integration of genomic, proteomic, and next-generation sequencing data to better understand disease progression. The article provides valuable insights for clinicians and researchers to optimize patient care and improve therapeutic strategies.

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