Your Global Genomics Partner for Research, Drug Discovery and Sequencing Solutions

Top genomics research service provider in San Francisco Bay Area. All projects executed and delivered out of our high-throughput sequencing lab in California.

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Considering Genomic Research?

 


MedGenome has a state-of-the-art sequencing facility with several sequencing machines including NovaSeq, MiSeq and 10X Chromium Controller and is committed to delivering the highest-quality NGS data with quick turnaround times using highly optimized protocols. Our team of scientists are dedicated to helping you find the right NGS solution for your research needs.

NGS Services

WGS/WES

Advance your cancer genetics, population genomics and genome-wide association studies with our whole genome, whole exome and custom targeted gene panel sequencing and analysis services for variant detection, de novo genome assembly, somatic mutation annotation and more.

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Bulk Transcriptomics

Analyze gene expression changes in your samples of interest in bulk or at single cell resolution using our RNA sequencing solutions. Our RNA sequencing processes are streamlined and rigorously validated across different species (prokaryote and eukaryote) and a wide range of samples (i.e. tissues, cells, FFPE).

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Single Cell Sequencing

MedGenome's single cell sequencing solutions enable high resolution analysis of your genomic data to gain insights into cellular heterogeneity and gene expression changes within distinct cell populations. We also offer multi-omic single cell solutions such as CITE-seq, immune repertoire profiling (VDJ-seq), single cell ATAC-seq & multiome sequencing.

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Immuno-oncology, Biomarker Discovery and Immune Profiling Solutions

TCR Sequencing

Our T-cell sequencing solutions enable identification of all potential clonotypes in a diverse repertoire of TCRs along with accurate data representation of functional and non-functional TCRs. We have developed proprietary assays for profiling the TCR repertoire in a number of species.

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BCR Sequencing

Our targeted B-cell sequencing solutions offer deep insights into B-cell differentiation, BCR somatic hypermutation, class switching, and antigen specificity. We offer both bulk and single cell BCR sequencing for several species including human, mouse and rat.

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Profiling the Tumor Microenvironment

Our patented OncoPeptTUME algorithm analyzes RNA-Seq data to produce a high-resolution mapping of the tumor microenvironment using proprietary cell type specific gene expression signatures. This provides a critical assessment of the inflammatory microenvironment that modulates T-cell infiltration and its anti-tumor activities to enable better prediction of treatment response and efficacy.

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Bioinformatics (BioFx) Services

BioFX Analysis Platform

Our robust in-house bioinformatics platform offers publication-ready, high-quality figures and comprehensive reports on a wide range of NGS data types. With a highly scalable analysis pipeline that utilizes the best-in-class bioinformatics tools, our highly skilled Bioinformatics team is ready to provide end-to-end project support.

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BioFX - Dedicated Bioinformatics Resources

Leverage our expert scientific team that has both a deep understanding of biology and the bioinformatics expertise required to handle complex genomics analysis projects. Our team can work with you to develop a customized plan that best suits your analysis needs.

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Genomic Data Visualization

Genomic data visualization is a critical component in genomics. Our analysis platform offers publication-ready analysis outputs with data-rich reports to help gain the most insights into your data.

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Specialized Services and Solutions

Antibody Discovery (HitMab)

Using our proprietary HiTMab (High Throughput Monoclonal antibody discovery) platform, we offer rapid end-to-end antibody discovery solutions for your antigen of interest.

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TSO 500 & TST 170

We offer Illumina’s TruSight Oncology 500 and TruSight Tumor 170 solutions that enable comprehensive genomic profiling of tumor samples. It is a single workflow identifying DNA and RNA variants from the same sample. It can detect Indels, SNVs, CNV, fusions and splice variants. Also it measures biomarkers like TMB and MSI.

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Epigenomics

We offer specialized end-to-end epigenomic solutions such as ATAC seq, CUT&TAG, CUT&RUN and single cell multiomics. Our streamlined processes ensure reproducible, high-quality interpretable data accompanied by a comprehensive data analysis report.

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MedGenome Sponsored Scientific Sessions

MedGenome scientists and the iReceptor Gateway team provide an overview of TCR data generation, analysis and how to leverage the iReceptor Gateway to annotate and interpret these data.
Aditya Pai and Dr. Kushal Suryamohan provide a detailed talk on MedGenome's advanced analysis methods for bulk and single cell transcriptomics data, and their application in understanding molecular and cellular mechanisms of disease.
Dr. Kushal Suryamohan provides an overview of our framework for scalable and reproducible analysis and visualization of a broad range of genomics data types including whole genome sequencing, transcriptomics, single cell genomics, immune profiling and genome assembly and annotation.

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Partner With Us

With expertise in sample & library preparation for various assays including whole exome, whole genome, transcriptome, single cell gene expression, TCR, CITE-seq, ATAC and CUT&TAG, MedGenome is able to partner with clients on biomarker identification and target discovery projects. Our advanced genomic data analysis capabilities and insights into South-Asian specific variants make us a preferred partner for bio-pharma clients.

We partner with clients in US, Central & South America, Canada and Europe.

Our genomics team is also able to partner with manufacturers to incorporate genetic insights into their assay development.

To know more about the value MedGenome provides to your research, click here

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