The power of single cell sequencing

Generate insights at a cellular level

Cells are fundamental units of all living organisms. The advent of single cell DNA sequencing technologies has revolutionized our understanding of the various cell types associated with different tissues. Access to single-cell resolution has enabled significant insights into disease pathology including immune cell infiltration in several cancer types and its consequence on therapeutic outcomes. MedGenome is a 10X certified single cell sequencing service provider that offers end-to-end solutions for single cell analysis. We also developed a suite of bioinformatics tools for the analysis, interpretation and visualization of single cell sequencing data including the identification of heavy and light chain pairs following BCR and TCR sequencing.

Our optimized workflows support processing of fresh or frozen cell suspensions, isolated cells in 96 well plates, and methanol fixed cells.

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We are a 10X certified single cell genomics service provider.

MedGenome has extensive experience in single cell gene expression analysis and multi-omics profiling using fresh cells/tissue samples, cryopreserved cells, nuclei isolated from frozen tissues and fixed cell/tissue samples. We also provide enhanced services such as cryopreservation of cells and post-submission dead cell removal to ensure the highest quality of data for your project.

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Featured webinar

Advanced analysis of bulk and single cell transcriptomics data

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Single cell sequencing services

Our comprehensive suite of single cell solutions has you covered

Gene expression

Explore cellular heterogeneity using 3' or 5' gene expression libraries for biomarker discovery and more.

Single cell immune profiling

Discover full length paired sequences for T and B cells repertoire analysis.
Simultaneously measure gene expression and immune repertoires combined with cell surface protein data to look at functional states and subsets of immune cells.

Multiome profiling

Combine gene expression with cell surface protein expression data for a multiomic view of your sample of interest.
Uncover gene regulatory programs by assaying the epigenome and gene expression simultaneously.

As an early adopter of single cell genomic sequencing, MedGenome supports your research needs from experimental design to data analysis, including selection of the appropriate single cell workflow. We have experience processing complex sample types that vary in quality and input quantity while ensuring fast turnaround times and data accuracy. Our analysis offerings include custom visualizations, bespoke workflows, external data integration and support for publication of data.

Single cell sequencing analysis

Comprehensive data analysis and interactive visualization powered by MAnGO

Visualize your data through MAnGO (MedGenome Analytics for Genomics), our proprietary analysis platform. This single cell analysis platform uses state-of-the-art analysis and visualization tools. Each report contains a comprehensive summary of key analysis findings with interactive plots and tables. Our reports also allow users to visualize the analysis results including UMAP plots of cell clustering, differential gene expression, pathway enrichment, RNA velocity & lineage analysis, and cell-cell communication analysis.

Our bioinformatics services include:

Streamlined on-premise and cloud-native analysis workflows for fast & scalable single cell sequencing protocol & analysis.
Customized interactive analysis reports.
Publication-ready figures.
Data interpretation with support from MedGenome's team of PhD-level experts.

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Reports customized to your needs

Comprehensive reports

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Advanced QC metrics

Digital gene expression and heatmap visualization

Interactive tSNE plots with cell type and cluster information

Single cell sequencing workflow

Workflow for sample processing and selection of single cell genomic sequencing applications at MedGenome

Fresh/cryopreserved samples with viable cells

Fixed tissues/cells/nuclei including FFPE

Service highlights

The MedGenome advantage

End-to-end solutions

for sample QC, viability assessment, single cell library preparation, sequencing and analysis.

Custom analytics

for your bioinformatics and data interpretation needs.

Expert team of biologists

available for consultation.

Resources

White papers and technical resources

Video

Single Cell Report Walkthrough

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Whitepaper

MedGenome's versatile single-cell solutions: advancing multiome analysis across diverse sample types

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services

Other services you'll be interested in

Transcriptomics services
Spatial transcriptomics
WGS/WES services
Immune profiling services

Transcriptomics services

Vast experience and expertise in generating high-quality data from degraded RNA samples.
Supported by custom and advanced bioinformatics analytics.

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Spatial transcriptomics

10X Visium for spatial transcriptome profiling of fresh frozen and FFPE tissue sections.
Tissue annotation supported by expert pathologists.

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WES/WGS

Cost effective whole genome/exome services with expedited turn-around times.

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Immuno-oncology solutions

Multi-species (human, mouse, rat and non-human primate) bulk and single cell TCR/BCR sequencing and bioinformatics services.

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TESTIMONIALS

"Always very quick responses, wonderful turnaround times and exemplary quality of service. Data is always great, and any issues are always resolved. The price is competitive, stable and reliable. There's no problem that the MedGenome team hasn't solved yet."

– Cassie Pond, The Feinstein Institutes for Medical Research

TESTIMONIALS

"We are examining the results. Very exciting. My compliments — you make the best summary report I have seen."

– Dr John Castle, Sr. Director, Bioinformatics, Agenus

TESTIMONIALS

"We have been working with MedGenome on identification of novel oncogenic mutations and exome anlaysis of tumor cells. Our collaboration has been extremely productive. We are extremely happy with their commitment towards research and development in general"

– Dr Krishnaraj Rajalingam, Heisenberg Professor in Cell Biology, Mainz University, Germany

TESTIMONIALS

"We have been working with MedGenome on genomics-based diagnostics and research for many years now. We are extremely happy and pleased with the quality, the skill and the pro-activeness of the firm. No wonder that it has grown to be a leading genomics service provider."

– Dr Radha Rama Venkatesan, Executive Scientific Officer, Molecular Genetics, MDRF

how to order

Starting a project with MedGenome

MedGenome's customer portal allows for easy sample submission and sample tracking during lab processing. Using our portal ensures data QC, raw data and interactive analysis reports are delivered securely.

Our process is simple