Next generation sequencing enables gene expression analysis from normal and disease tissues with high-sensitivity. Profiling of coding and non-coding RNAs is important in revealing molecular mechanisms of development and disease. With the several options that exist for gene expression profiling, it is also possible to perform whole transcriptome profiling ranging from a single-cell to thousands of cells in a sample. In addition, current methodologies allow for profiling of transcriptomes from intact RNA and RNA degraded due to the storage and isolation conditions (such as FFPE processed tissue blocks, cell-free nucleic acids etc). At MedGenome we offer solutions, for performing gene expression analysis from a wide-range of sample types. Shown in table 1 is a range of sample types that we process for whole transcriptome profiling.
Highlights of our services are:
Transcriptome Library Prep, Sequencing, and Analysis Service Offerings
|Source||Library Prep Options||Analysis Offering|
Standard Analysis Package
In addition to the NGS library preparation solutions, we offer extensive informatics solutions for whole-transcriptome profiling that ranges from standard gene expression analyses to advanced analyses of splicing, pathways, visualization and tertiary analyses to reveal heterogeneity and cell types in a population as well tumor microenvironment analyses. In addition to that we have solutions using machine learning approaches that utilize gene expression data to predict biomarkers and classify tissue types and diseases.