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Genome-Wide Polygenic Score Predicts Large Number of High Risk Individuals in Monogenic Undiagnosed Young Onset Parkinson’s Disease Patients from India

Advanced biology, Vol. 6, Issue 11, Pages e2101326, 2022

PMID: 35810474

Parkinson’s disease (PD) is a genetically heterogeneous neurodegenerative disease with poorly defined environmental influences. Genomic studies of PD patients have identified disease-relevant monogenic genes, rare variants of significance, and polygenic risk-associated variants.

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  https://www.ncbi.nlm.nih.gov/pubmed/35810474

 

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