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Non-coding and Coding Transcriptional Profiles Are Significantly Altered in Pediatric Retinoblastoma Tumors

Frontiers in oncology, Vol. 9, Pages 221, 2019

PMID: 31058073

Retinoblastoma is a rare pediatric tumor of the retina, caused by the homozygous loss of the Retinoblastoma 1 (RB1) tumor suppressor gene. Previous microarray studies have identified changes in the expression profiles of coding genes; however, our understanding of how non-coding genes change in this tumor is absent.

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  https://www.ncbi.nlm.nih.gov/pubmed/31058073

 

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