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South Asian Medical Cohorts Reveal Strong Founder Effects And High Rates Of Homozygosity

Nature communications, Vol. 14, Issue 1, Pages 3377, 2023

PMID: 37291107

The benefits of large-scale genetic studies for healthcare of the populations studied are well documented, but these genetic studies have traditionally ignored people from some parts of the world, such as South Asia. Here we describe whole genome sequence (WGS) data from 4806 individuals recruited from the healthcare delivery systems of Pakistan, India and Bangladesh, combined with WGS from 927 individuals from isolated South Asian populations.

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