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Validation of a Genome-Wide Polygenic Score for Coronary Artery Disease in South Asians

Journal of the American College of Cardiology, Vol. 76, Issue 6, Pages 703-714, 2020

PMID: 32762905

Genome-wide polygenic scores (GPS) integrate information from many common DNA variants into a single number. Because rates of coronary artery disease (CAD) are substantially higher among South Asians, a GPS to identify high-risk individuals may be particularly useful in this population.

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  https://www.ncbi.nlm.nih.gov/pubmed/32762905

 

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