Molecular Biology Services

Custom Monoclonal Antibodies

MedGenome offers production of high-affinity monoclonal reagent-grade Fabs and full-length IgGs for use in basic and clinical research labs. It uses licensed proprietary phage display libraries to generate synthetic Fabs/IgGs. The diversity of peptides displayed in the library is >10^10, which guarantees high affinity Fabs against antigens from any source.

  • Purified Ag protein (5mg/ml) can be supplied by customer against which Fab can be generated. Alternatively, customer can use our protein production pipeline to generate the antigen for screening.
  • Customer has the option to select Fabs or full-length IgGs, based on their requirement.
  • Option of getting the Ag-Fab or Ag-IgG validation assay optimised is available with us
  • Customer can choose Fc region of IgG (human/mouse/rat/goat/others (specify), depending on their application.
  • Customer has the ability to opt for any special detection tags on the Fabs/IgGs.
  • MedGenome Fabs/IgGs work best for FACS/IF/IP and ELISA and worth testing for WB and IHC.

Highlights

  • Monoclonal antibodies
  • Diversity
  • Choice of Format – Fab, IgG with mouse/rabbit/human Fc
  • TAT – antigen protein to antibody in 6 weeks!
  • Development using animal free process

 

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