DNA Sequencing
Genomic Research
Whole Genome and Exome Sequencing applications have been widely accepted for use in genome wide association studies for complex diseases, variant calling to identify clinically actionable mutations and other specialized areas like identification of mutations that accumulate and give rise of tumor neo-antigens and shared antigens. At MedGenome, we routinely perform Whole Genome Sequencing and Exome Sequencing and analyses using best practices.
Discover Your Application
Solutions for cells, blood, tissues, FFPE with varying quality and quantity inputs
Whole Genome
Illumina and Kapa Solutions
- Illumina DNA Prep
- Illumina and Kapa PCR-Free Prep
- Nextera XT DNA Library Prep
- Kapa HyperPrep
Whole Exome
Agilent, Kapa and IDT Solutions
- Agilent SureSelect - Human and Mouse
- Kapa HyperExome
- IDT and other kits avilable by request
Targeted
Illumina and Others
- Illumina TSO 500 & TST 170 Panels
- Off the shelf and custom targeted panels from Roche, IDT, Agilent, Swift and others
Service Highlights
- Support with experimental design and selection of appropriate workflow dependent on analysis needs
- Experienced in processing a wide range of sample types with options for low input and degraded samples
BioFX Genome Analysis
- Streamlined pipeline for fast & scalable analysis
- Customized reporting
- Interactive reports
- Publication-ready figures
- Improve data interpretation with support from MedGenome's team of experts
Explore Analysis Reports
BioFX’s genome analysis platform was built using state-of-the-art analysis tools for germline, low-frequency somatic variant analysis and annotation as well as structural variant, copy number variant analysis and annotation. We offer prebuilt and custom workflows to meet all analysis goals
Detailed data quality,
alignment and coverage stats
Distribution of
base changes
for SNVs
Circos plots for SNPs,
Indels, CNVs and SV
representation for
selected genes
Lollipop plots
showing variants
for genes
Explore
mutation signatures
Ordering and Data Delivery
MedGenome's customer portal allows for easy sample submission and sample tracking during lab processing. Data QC, raw data and interactive analysis reports are delivered securely through customer portal.
White Papers and Technical Resources
MedGenome Inc. Services with Illumina’s TruSight Oncology 500 (TSO 500)
Illumina’s TSO 500 is a comprehensive assay that enables comprehensive genomic profiling of tumor samples. It is a single workflow identifying DNA and RNA variants from the same sample. It can detect InDels, SNVs, CNV, fusions and splice variants. It also measures biomarkers like Tumor Mutational Burden (TMB) and Microsatellite Instability (MSI) using limited sample input. MedGenome uses propriety analysis pipeline along with Illumina’s Basespace platform to analyze data providing high sensitivity and specificity to provide a comprehensive cancer genomic profile.
Denovo Genome Assembly Solutions at MedGenome
This Whitepaper explores MedGenome's experience in genomics technologies for developing a comprehensive, customizable, high-quality genome assembly and annotation service.
MedGenome Inc. Broadens NGS offerings with Loop Genomics Metagenomics Service
The whitepaper discusses how MedGenome utilizes Loop Genomics technology for 16S long-read sequencing. This workflow covers the entire V1-V9 regions in a single read, classified at the species or genus level, with zero false-positive assignments
Whole-genome Sequencing/Whole-exome QC Report
In this QC report, we show representative sample QC, sequencing QC and mapping metrics that will be provided to the customer for whole genome/exome from genomic DNA isolated from cells, fresh-frozen and FFPE tissue types.
Company
Resources
Research
- Tumor Microenvironment Solutions
- Immune Profiling Services
- NGS Services
- BioFX Bioinformatics Services
- Antibody Discovery Services
Diagnostics
Contact